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BDBM206041 US9255103, 42

SMILES: CC1CN(Cc2cc(COc3ccccc3)nn12)C(=O)c1cccc(F)c1

InChI Key: InChIKey=ODYPDGIAGVNBAM-UHFFFAOYNA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 206041   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM206041
PNG
(US9255103, 42)
Show SMILES CC1CN(Cc2cc(COc3ccccc3)nn12)C(=O)c1cccc(F)c1
Show InChI InChI=1/C21H20FN3O2/c1-15-12-24(21(26)16-6-5-7-17(22)10-16)13-19-11-18(23-25(15)19)14-27-20-8-3-2-4-9-20/h2-11,15H,12-14H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 138n/an/a7.4n/a



Vanderbilt University

US Patent


Assay Description
HEK cells transfected with the human mGluR5a receptor (H10H cell line) were plated at 15,000 cells/well in clear-bottomed poly-D-lysine-coated assay ...


US Patent US9255103 (2016)


BindingDB Entry DOI: 10.7270/Q29S1PV6
More data for this
Ligand-Target Pair