BDBM20622 1-[4-(4-cyclopentylpiperazin-1-yl)phenyl]-2-(3-hydroxyphenyl)-1,2,3,4-tetrahydroisoquinolin-6-ol::Piperazine Derivative, 49

SMILES Oc1ccc2C(N(CCc2c1)c1cccc(O)c1)c1ccc(cc1)N1CCN(CC1)C1CCCC1

InChI Key InChIKey=JJRHZGGFNFBSQM-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20622   

TargetEstrogen receptor beta(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20622(1-[4-(4-cyclopentylpiperazin-1-yl)phenyl]-2-(3-hyd...)
Affinity DataIC50:  1.11E+3nM EC50:  268nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM20622(1-[4-(4-cyclopentylpiperazin-1-yl)phenyl]-2-(3-hyd...)
Affinity DataIC50:  123nM EC50:  19.6nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed