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BDBM207502 US9260439, 386

SMILES: Cc1n[nH]cc1C(=O)N1CC[C@@](C)(C1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1

InChI Key: InChIKey=PFQSTUFFPBCENX-DEOSSOPVSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 207502   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
p110alpha-iSH2 p85alpha Complex


(Homo sapiens (Human))
BDBM207502
PNG
(US9260439, 386)
Show SMILES Cc1n[nH]cc1C(=O)N1CC[C@@](C)(C1)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1
Show InChI InChI=1S/C24H30N10O2/c1-15-18(13-28-31-15)21(35)33-6-4-24(2,14-33)34-5-3-17-19(16-11-26-22(25)27-12-16)29-23(30-20(17)34)32-7-9-36-10-8-32/h11-13H,3-10,14H2,1-2H3,(H,28,31)(H2,25,26,27)/t24-/m0/s1
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
<0.0180n/an/an/an/an/an/an/an/a



Pfizer Inc

US Patent


Assay Description
PI3KA_Act: Genes encoding for full length p110alpha and p85alpha nSH-iSH2=niSH2 (p85a aminoacids 322-600) subunits of PI3Kalpha complex were subclone...


US Patent US9260439 (2016)


BindingDB Entry DOI: 10.7270/Q2VH5MPV
More data for this
Ligand-Target Pair