BDBM207842 US9266828, E
SMILES CC(C)[C@H](NS(=O)(=O)Cc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCc1ccc(cc1)C(N)=N
InChI Key InChIKey=PRSVXIFOXDFBKT-VXKWHMMOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 207842
Affinity DataKi: 300nMAssay Description:Inhibition of human furin using Pyr-RTKR-AMC as substrate preincubated for 30 mins followed by substrate addition and measured by fluorescence based ...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMpH: 7.5 T: 2°CAssay Description:Furin activity was measured in triplicate in wells of a 96-well plate in 0.2 ml 50 mM HEPES, pH 7.5, containing 1 mM CaCl2, 0.005% Brij-35 and 20% gl...More data for this Ligand-Target Pair