BDBM207842 US9266828, E

SMILES CC(C)[C@H](NS(=O)(=O)Cc1ccc(cc1)C(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=PRSVXIFOXDFBKT-VXKWHMMOSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 207842   

TargetFurin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM207842(US9266828, E)
Affinity DataKi:  300nMAssay Description:Inhibition of human furin using Pyr-RTKR-AMC as substrate preincubated for 30 mins followed by substrate addition and measured by fluorescence based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetFurin(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM207842(US9266828, E)
Affinity DataIC50:  300nMpH: 7.5 T: 2°CAssay Description:Furin activity was measured in triplicate in wells of a 96-well plate in 0.2 ml 50 mM HEPES, pH 7.5, containing 1 mM CaCl2, 0.005% Brij-35 and 20% gl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent