BDBM207990 (2-((4-Chlorobenzyl)oxy)phenyl)(5-(2-(methylamino)thiazol-4-yl)indolin-1-yl)methanone (Compound 2)

SMILES: CNc1nc(cs1)-c1ccc2N(CCc2c1)C(=O)c1ccccc1OCc1ccc(Cl)cc1

InChI Key: InChIKey=GOAZOFMNXDONAU-UHFFFAOYSA-N

Data: 11 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 207990   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase WNK1 [1-491] (Human)	BDBM207990 ((2-((4-Chlorobenzyl)oxy)phenyl)(5-(2-(methylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	180	n/a	n/a	n/a	n/a	7.5	n/a
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Serine/threonine-protein kinase WNK1 [1-491] (Human)	BDBM207990 ((2-((4-Chlorobenzyl)oxy)phenyl)(5-(2-(methylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	7.5	n/a
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Serine/threonine-protein kinase WNK1 [198-401] (Human)	BDBM207990 ((2-((4-Chlorobenzyl)oxy)phenyl)(5-(2-(methylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase WNK1 [198-401] (Human)	BDBM207990 ((2-((4-Chlorobenzyl)oxy)phenyl)(5-(2-(methylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Serine/threonine-protein kinase WNK1 [1-491] (Human)	BDBM207990 ((2-((4-Chlorobenzyl)oxy)phenyl)(5-(2-(methylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	64	n/a	n/a	n/a	n/a	7.3	n/a
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Serine/threonine-protein kinase WNK2 [166-489] (Human)	BDBM207990 ((2-((4-Chlorobenzyl)oxy)phenyl)(5-(2-(methylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	7.3	n/a
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Serine/threonine-protein kinase WNK3 [1-434] (Human)	BDBM207990 ((2-((4-Chlorobenzyl)oxy)phenyl)(5-(2-(methylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	377	n/a	n/a	n/a	n/a	7.3	n/a
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Serine/threonine-protein kinase WNK4 [1-444] (Human)	BDBM207990 ((2-((4-Chlorobenzyl)oxy)phenyl)(5-(2-(methylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	187	n/a	n/a	n/a	n/a	7.3	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase WNK1 (Human)	BDBM207990 ((2-((4-Chlorobenzyl)oxy)phenyl)(5-(2-(methylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase WNK1 (Human)	BDBM207990 ((2-((4-Chlorobenzyl)oxy)phenyl)(5-(2-(methylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 12 member 2 (Human)	BDBM207990 ((2-((4-Chlorobenzyl)oxy)phenyl)(5-(2-(methylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair