BDBM207991 ML348

SMILES: c1cc(oc1)C(=O)N2CCN(CC2)CC(=O)Nc3cc(ccc3Cl)C(F)(F)F

InChI Key: InChIKey=OXKNHBBDOIMFFQ-UHFFFAOYSA-N

Data: 17 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 207991   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-protein thioesterase 1 (Human)	BDBM207991 (ML348) Show SMILES Show InChI	GoogleScholar	UniChem		280	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acyl-protein thioesterase 1 (Human)	BDBM207991 (ML348) Show SMILES Show InChI	GoogleScholar	UniChem		280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acyl-protein thioesterase 1 (Human)	BDBM207991 (ML348) Show SMILES Show InChI	GoogleScholar	UniChem		300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acyl-protein thioesterase 1 [L176M] (Human)	BDBM207991 (ML348) Show SMILES Show InChI	GoogleScholar	UniChem		340	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acyl-protein thioesterase 1 [Q83P] (Human)	BDBM207991 (ML348) Show SMILES Show InChI	GoogleScholar	UniChem		370	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acyl-protein thioesterase 2 [L78I,A85S,P86Q,H152R,R153A,A154S] (Human)	BDBM207991 (ML348) Show SMILES Show InChI	GoogleScholar	UniChem		430	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acyl-protein thioesterase 1 [I75L,S82A] (Human)	BDBM207991 (ML348) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acyl-protein thioesterase 1 [I75L] (Human)	BDBM207991 (ML348) Show SMILES Show InChI	GoogleScholar	UniChem		2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acyl-protein thioesterase 2 [L78I,A85S,P86Q] (Human)	BDBM207991 (ML348) Show SMILES Show InChI	GoogleScholar	UniChem		3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acyl-protein thioesterase 2 [L78I] (Human)	BDBM207991 (ML348) Show SMILES Show InChI	GoogleScholar	UniChem		5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acyl-protein thioesterase 2 [L78I,A85S] (Human)	BDBM207991 (ML348) Show SMILES Show InChI	GoogleScholar	UniChem		6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acyl-protein thioesterase 1 [I75L,S82A,Q83P] (Human)	BDBM207991 (ML348) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acyl-protein thioesterase 1 [I75L,S82A,Q83P,R149H,A150R,S151A] (Human)	BDBM207991 (ML348) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acyl-protein thioesterase 2 (Human)	BDBM207991 (ML348) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acyl-protein thioesterase 2 [M178L] (Human)	BDBM207991 (ML348) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acyl-protein thioesterase 2 [P86Q] (Human)	BDBM207991 (ML348) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acyl-protein thioesterase 2 [H152R] (Human)	BDBM207991 (ML348) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	6.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acyl-protein thioesterase 2 (Human)	BDBM207991 (ML348) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair