BDBM20878 (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{2-[(4-methoxyphenyl)methyl]phenoxy}oxane-3,4,5-triol::CHEMBL270766::O-glucoside, 4a
SMILES COc1ccc(Cc2ccccc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1
InChI Key InChIKey=HFLCZNNDZKKXCS-OUUBHVDSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 20878
Affinity DataKi: 2.40nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Inhibition of human kidney SGLT2 assessed as renal glucose reabsorptionMore data for this Ligand-Target Pair
Affinity DataKi: 708nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells by [14C]AMG uptake assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells by [14C]AMG uptake assayMore data for this Ligand-Target Pair
Affinity DataEC50: >8.00E+3nMAssay Description:Inhibition of SGLT1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 9.20nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
Affinity DataEC50: >8.00E+3nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataEC50: 9.20nMpH: 7.2 T: 2°CAssay Description:Inhibitors were assayed for the ability to inhibit [14C]AMG uptake in a protein-free buffer over a 2 h incubation period. The response curve was fitt...More data for this Ligand-Target Pair
Affinity DataIC50: 6.25nMAssay Description:Inhibition of human recombinant SGLT2 expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair