BDBM20880 (2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-6-(hydroxymethyl)oxane-3,4,5-triol::BMS-512148::C-aryl glucoside, 6::CHEMBL429910::Dapagliflozin

SMILES: CCOc1ccc(cc1)Cc2cc(ccc2Cl)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O

InChI Key: InChIKey=JVHXJTBJCFBINQ-UHFFFAOYSA-N

Data: 53 IC50  12 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 65 hits for monomerid = 20880   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Rat)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier family 5 member 4 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/myo-inositol cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	429	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	593	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	891	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.39E+3	n/a	n/a	7.2	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	803	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	629	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	860	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Human)	BDBM20880 (CHEMBL429910 | C-aryl glucoside, 6 | BMS-512148 | ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.10	n/a	n/a	7.2	22
TBA									Citation and Details
					More data for this Ligand-Target Pair