BDBM20886 3-(5-chloro-2,4-dihydroxyphenyl)-4-{4-[(1,1-dioxo-1,4-thiomorpholin-4-yl)methyl]phenyl}-N-ethyl-1H-pyrazole-5-carboxamide::Pyrazole, 19d

SMILES CCNC(=O)c1[nH]nc(c1-c1ccc(CN2CCS(=O)(=O)CC2)cc1)-c1cc(Cl)c(O)cc1O

InChI Key InChIKey=TYBUCKMEAMKGDB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 20886   

TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM20886(3-(5-chloro-2,4-dihydroxyphenyl)-4-{4-[(1,1-dioxo-...)
Affinity DataIC50: 27nM EC50:  826nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed