BDBM20933 3,6-dimethyl-4-(pentan-3-yloxy)-2-(2,4,6-trimethylphenoxy)pyridine::CP-316311::JMC511377 Compound 2

SMILES CCC(CC)Oc1cc(C)nc(Oc2c(C)cc(C)cc2C)c1C

InChI Key InChIKey=ZSEJGVQTBLJRCQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 20933   

LigandPNGBDBM20933(JMC511377 Compound 2 | 3,6-dimethyl-4-(pentan-3-yl...)
Affinity DataIC50: 6.80nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20933(JMC511377 Compound 2 | 3,6-dimethyl-4-(pentan-3-yl...)
Affinity DataIC50: 6.80nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM20933(JMC511377 Compound 2 | 3,6-dimethyl-4-(pentan-3-yl...)
Affinity DataIC50: 92nMAssay Description:Displacement of ovine [125I]CRF from human CRF1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed