BDBM209776 US9273033, 76
SMILES Cc1ncc(c(OC[C@H]2C[C@@H]2c2ccc3ccccc3n2)n1)-c1cc(=O)n(C)cc1C
InChI Key InChIKey=MHCKKOXXKKOVIW-QUCCMNQESA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 209776
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 0.0350nM ΔG°: -14.3kcal/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP FP kit supplied by Molecular Devices, Sunnyv...More data for this Ligand-Target Pair