BDBM210070 US9270353, 17

SMILES: C[C@]1(C=CSC(=N1)N)c2cc(ccc2F)NC(=O)c3ccc(cn3)C#N

InChI Key: InChIKey=VLLFGVHGKLDDLW-UHFFFAOYSA-N

Data: 2 KI  15 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 210070   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin E (Human)	BDBM210070 (US9270353, 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Human)	BDBM210070 (US9270353, 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM210070 (US9270353, 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM210070 (US9270353, 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM210070 (US9270353, 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM210070 (US9270353, 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM210070 (US9270353, 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Human)	BDBM210070 (US9270353, 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	5.0	n/a
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Cathepsin D (Human)	BDBM210070 (US9270353, 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 2 (Human)	BDBM210070 (US9270353, 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM210070 (US9270353, 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Mouse)	BDBM210070 (US9270353, 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM210070 (US9270353, 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Human)	BDBM210070 (US9270353, 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Human)	BDBM210070 (US9270353, 17) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Human)	BDBM210070 (US9270353, 17) Show SMILES Show InChI	GoogleScholar	UniChem		0.130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 2 (Human)	BDBM210070 (US9270353, 17) Show SMILES Show InChI	GoogleScholar	UniChem		185	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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