BDBM21025 (2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanamido]-4-methylpentanoic acid::(D-Ala2,D-Leu5)-Enkephalin::BW-180C::CHEMBL340032::DADLE::DADLE-OH::H-Tyr-D-Ala-Gly-Phe-D-Leu-OH::[D-Ala2-D-Leu5]enkephalin

SMILES: CC(C)C[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O

InChI Key: InChIKey=ZHUJMSMQIPIPTF-UHFFFAOYSA-N

Data: 32 KI  15 IC50  5 Kd  6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 58 hits for monomerid = 21025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Rat)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	129	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Mouse)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Guinea pig)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rat)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rat)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	625	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1 (Rat)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Guinea pig)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Mouse)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	447	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.0200	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Guinea pig)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rat)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Guinea pig)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Mouse)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	447	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Guinea pig)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Guinea pig)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Mouse)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	54	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1 (Mouse)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1 (Mouse)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rat)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Pig)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		0.740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30	-12.1	n/a	n/a	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Mouse)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		1.65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Opioid receptor delta 1 (Bovine)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Mouse)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		1.83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Pig)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Mouse)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		2.49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		2.85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Guinea pig)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Guinea pig)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Bovine)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rat)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rat)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Opioid receptor delta 1 (Bovine)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		10.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Bovine)	BDBM21025 ([D-Ala2-D-Leu5]enkephalin | (D-Ala2,D-Leu5)-Enkeph...) Show SMILES Show InChI	GoogleScholar	UniChem		14.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair