BDBM210853 US9290467, 23

SMILES: c1cc2c(cc1C[C@H](NC(=O)c3ccc(cc3OCCCCO2)C(F)(F)F)C(=O)NC4(CC4)C#N)Cl

InChI Key: InChIKey=XAPRSGPLBWSEHV-UHFFFAOYSA-N

Data: 2 KI  7 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 210853   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Procathepsin L (Human)	BDBM210853 (US9290467, 23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	6.5	n/a
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Cytochrome P450 3A4 (Human)	BDBM210853 (US9290467, 23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM210853 (US9290467, 23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin B (Human)	BDBM210853 (US9290467, 23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin L2 (Human)	BDBM210853 (US9290467, 23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM210853 (US9290467, 23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin S (Human)	BDBM210853 (US9290467, 23) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Procathepsin L (Human)	BDBM210853 (US9290467, 23) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM210853 (US9290467, 23) Show SMILES Show InChI	GoogleScholar	UniChem		11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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