BDBM211634 US9290457, Example 4.18

SMILES CCOC(=O)C1=C(C)N(C(=O)N(C)C1c1ccc(cc1C(=O)NC1CCN(C)C1)C#N)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=YDKVGUAFSPSFKS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 211634   

TargetNeutrophil elastase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM211634(US9290457, Example 4.18)
Affinity DataIC50: 1.30nMpH: 7.5 T: 2°CAssay Description:Materials: Human neutrophil elastase was purchased from Calbiochem (Cat. No.: 324681) and the elastase substrate MeOSuc-Ala-Ala-Pro-Val-AMC from Bach...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent