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BDBM211960 US9290481, 4.2

SMILES: Cc1c[nH]c2c(Nc3nc(N[C@@H]4CCCC[C@@H]4N)cnc3C(N)=O)cccc12

InChI Key: InChIKey=ZVFJBVQLKDPCSZ-DUXBJXIBNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 211960   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase SYK


(Homo sapiens (Human))
BDBM211960
PNG
(US9290481, 4.2)
Show SMILES Cc1c[nH]c2c(Nc3nc(N[C@@H]4CCCC[C@@H]4N)cnc3C(N)=O)cccc12
Show InChI InChI=1/C20H25N7O/c1-11-9-23-17-12(11)5-4-8-15(17)26-20-18(19(22)28)24-10-16(27-20)25-14-7-3-2-6-13(14)21/h4-5,8-10,13-14,23H,2-3,6-7,21H2,1H3,(H2,22,28)(H2,25,26,27)/t13-,14+/s2
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/a7.530



Novartis AG

US Patent


Assay Description
All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...


US Patent US9290481 (2016)


BindingDB Entry DOI: 10.7270/Q2G15ZPR
More data for this
Ligand-Target Pair