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BDBM212386 US9550778, chem-us-00228

SMILES: Cc1cc(-c2cc(C(=O)Nc3ccc(F)cn3)c3ncnn3c2)n(C)n1

InChI Key: InChIKey=GXLHBIZYKOXUPO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 212386   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor


(Rattus norvegicus (Rat))
BDBM212386
PNG
(US9550778, chem-us-00228)
Show SMILES Cc1cc(-c2cc(C(=O)Nc3ccc(F)cn3)c3ncnn3c2)n(C)n1
Show InChI InChI=1S/C17H14FN7O/c1-10-5-14(24(2)23-10)11-6-13(16-20-9-21-25(16)8-11)17(26)22-15-4-3-12(18)7-19-15/h3-9H,1-2H3,(H,19,22,26)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 2.13E+3n/an/an/an/a7.425



Vanderbilt University

US Patent


Assay Description
The following examples of the in vitro effects of the disclosed compounds are prophetic. An example of an in vitro assay method for assessing the rec...


US Patent US9550778 (2017)


BindingDB Entry DOI: 10.7270/Q24M96J4
More data for this
Ligand-Target Pair