BDBM212434 (2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydrochromen-4-one::Dihydromyricetin (diH-Myr)

SMILES O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c1cc(O)c(O)c(O)c1

InChI Key InChIKey=KJXSIXMJHKAJOD-LSDHHAIUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 212434   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM212434((2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl...)
Affinity DataIC50:  1.28E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation by Thioflavin-T fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Barcelona

Curated by ChEMBL
LigandPNGBDBM212434((2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl...)
Affinity DataIC50:  2.53E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence intensity was measured at 420 nm excitation and 485 nm emission using a microplate reader (MPR-A4ιII; TOSOH, Tokyo, Japan, or Fluoroska...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed