BDBM212601 US9556111, Table 1.6::US9951033, Compound Table 1.8

SMILES: OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2cccc(c2)C(F)(F)F)n1

InChI Key: InChIKey=ADYOZMCLOMXFIN-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 212601   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A-kinase anchor protein 7 isoform gamma (AKAP-18) (Mus musculus (Mouse))	BDBM212601 (US9556111, Table 1.6 | US9951033, Compound Table 1...) Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2cccc(c2)C(F)(F)F)n1 Show InChI InChI=1S/C20H16F4N2O2S/c21-16-6-4-13(5-7-16)9-26(11-18-25-17(12-29-18)19(27)28)10-14-2-1-3-15(8-14)20(22,23)24/h1-8,12H,9-11H2,(H,27,28)	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.05E+4	n/a	n/a	n/a	n/a
UNIVERSITETET I OSLO US Patent					Assay Description Stable and optimal assay conditions were determined by cross-titrating GST-AKAP18 δ and biotinylated PLB using 10 μg/ml glutathione accepto...				US Patent US9951033 (2018) BindingDB Entry DOI: 10.7270/Q2HQ4270
					More data for this Ligand-Target Pair
A-kinase anchor protein 7 isoform gamma (Homo sapiens (Human))	BDBM212601 (US9556111, Table 1.6 | US9951033, Compound Table 1...) Show SMILES OC(=O)c1csc(CN(Cc2ccc(F)cc2)Cc2cccc(c2)C(F)(F)F)n1 Show InChI InChI=1S/C20H16F4N2O2S/c21-16-6-4-13(5-7-16)9-26(11-18-25-17(12-29-18)19(27)28)10-14-2-1-3-15(8-14)20(22,23)24/h1-8,12H,9-11H2,(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.05E+4	n/a	n/a	n/a	n/a
UNIVERSITETET I OSLO US Patent					Assay Description Stable and optimal assay conditions were determined by cross-titrating GST-AKAP18δ and biotinylated PLB using 10 μg/ml glutathione acceptor...				US Patent US9556111 (2017) BindingDB Entry DOI: 10.7270/Q20Z758K
					More data for this Ligand-Target Pair