BDBM21281 (11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphthalen-1-ylcarbonyl)-9-oxa-1-azatricyclo[6.3.1.0^{4,12}]dodeca-2,4(12),5,7-tetraene::(2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl)methanone monomethanesulfonat::CHEMBL188::WIN 55,212-2::WIN 55212-2::WIN-55212::WIN55212-2

SMILES: Cc1c(c2cccc3c2n1[C@@H](CO3)CN4CCOCC4)C(=O)c5cccc6c5cccc6

InChI Key: InChIKey=HQVHOQAKMCMIIM-UHFFFAOYSA-N

Data: 166 KI  15 IC50  31 EC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 211 hits for monomerid = 21281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rat)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	143	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Mouse)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rat)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rat)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	37	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.390	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rat)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Rat)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	86	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	24.6	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	24.6	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Mouse)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	204	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.470	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	37.6	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	112	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	89.6	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15.7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	89.6	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	50.1	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1/2 (Rat)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1/2 (Rat)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.56	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rat)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Human)	BDBM21281 (WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...) Show SMILES Show InChI	GoogleScholar	UniChem		0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair