BDBM213248 6-{[(1r)-1- cyclobutylethyl]amino}- 8-(4-cyclobutylpyridin-2- yl)-7-[4- (trifluoromethyl)benzyl]- 7h-purine-2-carboxylic acid::US9540377, 1.54
SMILES C[C@@H](Nc1nc(nc2nc(-c3cc(ccn3)C3CCC3)n(Cc3ccc(cc3)C(F)(F)F)c12)C(O)=O)C1CCC1
InChI Key InChIKey=LKMVPAHJPSJAJM-MRXNPFEDSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 213248
Affinity DataIC50: 5.61nMT: 2°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair