BDBM213667 US9278981, 259

SMILES NC1CN(C1)c1ncc(cc1-c1cncnc1)C(=O)Nc1ccc(OC(F)(F)Cl)cc1

InChI Key InChIKey=YQCHJORSBGANNU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 213667   

TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM213667(US9278981, 259)
Affinity DataIC50: <0.130nMpH: 7.5 T: 2°CAssay Description:The assay plates were prepared by addition of 50 nL per well of compound solution in 90% DMSO. The kinase reactions were started by stepwise addition...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM213667(US9278981, 259)
Affinity DataIC50:  5.10nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent