BDBM21369 6-[4-(2-methylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide::CHEMBL222755::Piperazinehexanamide derivative, 7
SMILES Cc1ccccc1N1CCN(CCCCCC(=O)NC2CCCc3ccccc23)CC1
InChI Key InChIKey=JINXBCRENWAIPY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 21369
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 15.2nM ΔG°: -11.1kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 15.2nMAssay Description:Displacement of [3H]LSD from rat recombinant 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 143nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
Affinity DataKi: 262nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in Wistar Han rat cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 262nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
Affinity DataKi: 279nMAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
Affinity DataKi: 279nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Wistar Han rat hippocampal membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 1.82E+3nMAssay Description:Activity at 5HT7 receptor assessed as relaxation of substance P-induced contraction of Dunkin-Hartley guinea pig ileumMore data for this Ligand-Target Pair