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BDBM214235 US9283222, 298

SMILES: Fc1ccc(Cc2n[nH]c(=O)c3CCCCc23)cc1N1C(=O)C2CCCCC2C1=O

InChI Key: InChIKey=ZPSKESNMCAXCEZ-UHFFFAOYNA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 214235   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))
BDBM214235
PNG
(US9283222, 298)
Show SMILES Fc1ccc(Cc2n[nH]c(=O)c3CCCCc23)cc1N1C(=O)C2CCCCC2C1=O
Show InChI InChI=1/C23H24FN3O3/c24-18-10-9-13(11-19-14-5-1-2-6-15(14)21(28)26-25-19)12-20(18)27-22(29)16-7-3-4-8-17(16)23(27)30/h9-10,12,16-17H,1-8,11H2,(H,26,28)
PDB
MMDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
2n/an/an/an/an/an/a8.0n/a



AbbVie Inc

US Patent


Assay Description
PARP1 assay was conducted in PARP assay buffer containing 50 mM Tris pH 8.0, 1 mM DTT, 4 mM MgCl2. PARP reactions contained 1.5 uM [3H]-NAD+ (1.6 uCi...


US Patent US9283222 (2016)


BindingDB Entry DOI: 10.7270/Q2BZ64XD
More data for this
Ligand-Target Pair