BDBM21464 2-benzyl-3-{[1-(2-acetamido-4-methylpentanoyl)pyrrolidin-2-yl](hydroxy)phosphoryl}propanoic acid::Phosphinic Peptide Inhibitor, 28 FII::The second fraction of the HPLC chromatogram.

SMILES CC(C)CC(NC(C)=O)C(=O)N1CCC=C1P(O)(O)CC(Cc1ccccc1)C(O)=O

InChI Key InChIKey=JNRYHIIHOXLMCO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21464   

TargetAngiotensin-converting enzyme 2(Homo sapiens (Human))
University Of Athens

LigandPNGBDBM21464(2-benzyl-3-{[1-(2-acetamido-4-methylpentanoyl)pyrr...)
Affinity DataKi:  0.130nM ΔG°:  -13.5kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase A1(Bos taurus (bovine))
University Of Athens

LigandPNGBDBM21464(2-benzyl-3-{[1-(2-acetamido-4-methylpentanoyl)pyrr...)
Affinity DataKi:  0.5nMAssay Description:Inhibitor potencies toward bovine carboxypeptidase A (Sigma-Aldrich Co) were determined in 96-well microplates format. Activity was monitored by meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
University Of Athens

LigandPNGBDBM21464(2-benzyl-3-{[1-(2-acetamido-4-methylpentanoyl)pyrr...)
Affinity DataKi: >1.00E+4nM ΔG°: >-6.82kcal/molepH: 6.8 T: 2°CAssay Description:Continuous assays were performed by recording the fluorescence increase at 405 nm (excitation@ 320 nm) induced by the cleavage of fluorogenic substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed