BDBM214799 1xx
InChI string: InChI=1/C24H22ClF3N2O2/c25-20-10-9-17(13-19(20)24(26,27)28)29-22(31)18-8-4-7-16-11-12-30(23(32)21(16)18)14-15-5-2-1-3-6-15/h1-7,9-10,13,16,18,21H,8,11-12,14H2,(H,29,31)/t16-,18-,21+/s2
SMILES: FC(F)(F)c1cc(NC(=O)[C@H]2CC=C[C@H]3CCN(Cc4ccccc4)C(=O)[C@@H]23)ccc1Cl
InChI Key: InChIKey=BSPPZJZWKVYWNH-DUUNOXSYNA-N
Target (Institution) | Ligand | Target Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
κ opioid receptor (KOR D138N) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR M142A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR D138A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR K227A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR H291F) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR L212A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR E297A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR K200A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR M226A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (human)) | BDBM214799![]() (1xx) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR I135A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y139F) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y312F) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y139A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR H291A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y312A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y320F) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR I294A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y313F) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 510 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y119F) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 520 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y66A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 550 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Q115A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 580 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR I316A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 890 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y313A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y320A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y119A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y119F) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 140 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR I135A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR D138A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 36 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR D138N) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 9.10 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y139A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 400 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR M142A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 28 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR K200A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 80 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR L212A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR M226A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 43 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR K227A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 220 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR H291A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 890 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR H291F) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 230 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR I294A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 350 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR E297A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 65 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y312A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 360 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y312F) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 71 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y313A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 320 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y313F) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 58 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR I316A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 400 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y119A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 590 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Q115A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 72 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y66A) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 150 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (human)) | BDBM214799![]() (1xx) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 51 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
κ opioid receptor (KOR Y320F) (Homo sapiens (Human)) | BDBM214799![]() (1xx) | PDB GoogleScholar AffyNet ![]() | PC cid PC sid UniChem AffyNet ![]() | Article PubMed | n/a | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a |
University of North Carolina School of Medicine | Assay Description HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described... | J Biol Chem 288: 34470-83 (2013) | |||||||||||
More data for this Ligand-Target Pair |
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