BDBM21543 2-{1'-benzyl-5-chloro-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione}acetic acid::Spiro-indolinone analogue, 5

SMILES OC(=O)CN1C(=O)C2(CC(=O)N(Cc3ccccc3)C2=O)c2cc(Cl)ccc12

InChI Key InChIKey=ZCDQMYGMUJCSPB-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21543   

TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

LigandPNGBDBM21543(2-{1'-benzyl-5-chloro-1,2-dihydrospiro[indole-3,3'...)
Affinity DataKi:  150nM ΔG°:  -9.21kcal/molepH: 7.4 T: 2°CAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21543(2-{1'-benzyl-5-chloro-1,2-dihydrospiro[indole-3,3'...)
Affinity DataKi:  196nM ΔG°:  -9.05kcal/mole EC50:  418nMpH: 7.4 T: 2°CAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed