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BDBM215521 US9296745, 77

SMILES: O=C([C@@H]1CCCN(C1)c1ccc2nc([nH]c2n1)C1(CC1)n1cc(cn1)C1CC1)N1CCCC1

InChI Key: InChIKey=NZUUNTUORYNILF-LGWFVXIRNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 215521   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Diacylglycerol O-acyltransferase 2


(Homo sapiens (Human))
BDBM215521
PNG
(US9296745, 77)
Show SMILES O=C([C@@H]1CCCN(C1)c1ccc2nc([nH]c2n1)C1(CC1)n1cc(cn1)C1CC1)N1CCCC1
Show InChI InChI=1/C25H31N7O/c33-23(30-11-1-2-12-30)18-4-3-13-31(15-18)21-8-7-20-22(28-21)29-24(27-20)25(9-10-25)32-16-19(14-26-32)17-5-6-17/h7-8,14,16-18H,1-6,9-13,15H2,(H,27,28,29)/t18-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 107n/an/an/an/a7.425



Pfizer Inc

US Patent


Assay Description
For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 uL. To 1 uL of c...


US Patent US9296745 (2016)


BindingDB Entry DOI: 10.7270/Q25719VW
More data for this
Ligand-Target Pair