BDBM21667 N-[4-(hydroxymethyl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T0901317 analogue, 6

SMILES OCc1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1

InChI Key InChIKey=GNQJQTSRHDQFTL-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21667   

TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

LigandPNGBDBM21667(N-[4-(hydroxymethyl)phenyl]-N-(2,2,2-trifluoroethy...)
Affinity DataIC50:  7.94E+3nM EC50:  1.00E+4nMpH: 8.0 T: 2°CAssay Description:Polylysine YiO imaging beads (Amersham, GE Healthcare) were coated with histidine-tagged WT PXR LBD. Nonspecific binding sites were blocked with BSA....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM21667(N-[4-(hydroxymethyl)phenyl]-N-(2,2,2-trifluoroethy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H2]-25-hydroxycholesterol from N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial express...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM21667(N-[4-(hydroxymethyl)phenyl]-N-(2,2,2-trifluoroethy...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inverse agonist activity at N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial expression system assessed a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed