BDBM21675 (4R)-4-[(1S,2S,5R,7S,8R,9R,10S,11S,14R,15R)-8-ethyl-5,9-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanoic acid::6-ECDCA::6-ethyl chenodeoxycholic acid::6-ethyl-3,7-dihydroxycholan-24-oic acid::6ECDCA::6alpha-Ethyl-Chenodeoxycholic Acid::INT-747::INT747::Ocaliva::US10208081, E6-ECDCA::US10266560, Example 6-ECDCA::US11208418, Example Obeticholic::obeticholic acid

SMILES: C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI Key: InChIKey=BHQCQFFYRZLCQQ-UHFFFAOYSA-N

Data: 46 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 46 hits for monomerid = 21675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	99	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	99	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	85	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled bile acid receptor 1 (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	99	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	670	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	670	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	360	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled bile acid receptor 1 (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	99	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled bile acid receptor 1 (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	99	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	98	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	99	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled bile acid receptor 1 (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	85	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.90E+4	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	99	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	550	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled bile acid receptor 1 (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	755	n/a	n/a	7.2	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	361	n/a	n/a	7.2	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	550	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	75	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled bile acid receptor 1 (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	918	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
TBA									Citation and Details
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G-protein coupled bile acid receptor 1 (Mouse)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.74E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled bile acid receptor 1 (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	840	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	550	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	85	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled bile acid receptor 1 (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	290	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	710	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled bile acid receptor 1 (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21675 (6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	324	n/a	n/a	n/a	n/a
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