BDBM21690 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid::1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid::Bay 09867::CHEMBL8::Ciprinol::Cipro::Ciprofloxacin::US11590142, Compound Ciprofloxacin::US20250136618, Compound Ciprofloxacin::US9138393, Ciprofloxacin HCl::US9144538, Ciprofloxacin HCl

SMILES: c1c2c(cc(c1F)N3CCNCC3)N(C=C(C2=O)C(=O)O)C4CC4

InChI Key: InChIKey=MYSWGUAQZAJSOK-UHFFFAOYSA-N

Data: 2 KI  115 IC50  1 Kd  1 EC50

PDB links: 8 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 119 hits for monomerid = 21690   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 4 subunit A [V210L]/B (Bacillus subtilis-Bacillus subtilis (strain 168))	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	7.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Bacillus subtilis (strain 168))	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	7.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA helicase [35-727] (malaria parasite P. falciparum)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	8.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase inhibitor (Escherichia coli (strain K12))	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	233	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase A/A/B/B tetramer (Escherichia coli (strain K12))	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	233	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 4 subunit A/B (Escherichia coli (strain K12))	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 2 (Human)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Human)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 4 (Human)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Human)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.56E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Staphylococcus aureus)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase A/A/B/B tetramer (Escherichia coli (strain K12))	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Escherichia coli (strain K12))	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase A/A/B/B tetramer (Escherichia coli (strain K12))	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase A/A/B/B tetramer (Escherichia coli (strain K12))	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase A/A/B/B tetramer (Escherichia coli (strain K12))	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.07E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus subsp. aureus Mu50)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 4 subunit A (Staphylococcus aureus)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Staphylococcus aureus subsp. aureus Mu50)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Staphylococcus aureus)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Staphylococcus aureus)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>7.72E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Escherichia coli (strain K12))	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.01E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Escherichia coli (strain K12))	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Escherichia coli (strain K12))	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Staphylococcus aureus)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.66E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase A/A/B/B tetramer (Escherichia coli (strain K12))	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholesterol side-chain cleavage enzyme, mitochondrial (Rat)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	603	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Human)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.54E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.21E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 4 subunit A (Escherichia coli (strain K12))	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Escherichia coli (strain K12))	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA topoisomerase 4 subunit A (Staphylococcus aureus)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Staphylococcus aureus)	BDBM21690 (Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.87E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair