BDBM21692 1-(4-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(propan-2-yl)-2,3-dihydro-1H-pyrazol-4-yl]urea::1-(4-chlorophenyl)-3-[1-methyl-5-(1-methylethyl)-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl]urea::CHEMBL379761::Pyrazolone, 1

SMILES CC(C)c1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(-c2ccccc2)n1C

InChI Key InChIKey=PAEBEUZTAPIOIO-UHFFFAOYSA-N

Data  6 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 21692   

TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21692(1-(4-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(p...)
Affinity DataEC50:  44nMpH: 7.2 T: 2°CAssay Description:hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...More data for this Ligand-Target Pair
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21692(1-(4-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(p...)
Affinity DataEC50:  44nMAssay Description:Activity at human FPRL1-mediated calcium mobilization in CHO cellsMore data for this Ligand-Target Pair
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM21692(1-(4-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(p...)
Affinity DataEC50:  32nMAssay Description:Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM21692(1-(4-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(p...)
Affinity DataEC50:  51nMAssay Description:Biased agonist activity at human FPR1 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21692(1-(4-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(p...)
Affinity DataEC50:  41nMAssay Description:Biased agonist activity at human FPR2 expressed in FlpIn-CHO cells assessed as stimulation of ERK1/2 phosphorylation measured after 7 mins by Alphasc...More data for this Ligand-Target Pair
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM21692(1-(4-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(p...)
Affinity DataEC50:  95nMAssay Description:Biased agonist activity at human FPR2 expressed in FlpIn-CHO cells assessed as intracellular calcium mobilization by Fluo-4-AM dye based fluorescence...More data for this Ligand-Target Pair