BDBM21724 3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}phenyl)ethenyl]benzoic acid::3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazol-4-yl]methoxy}phenyl)ethenyl]benzoic acid::CHEMBL318457::GW-4064

SMILES: CC(C)c1onc(c1COc1ccc(\C=C\c2cccc(c2)C(O)=O)c(Cl)c1)-c1c(Cl)cccc1Cl

InChI Key: InChIKey=BYTNEISLBIENSA-UHFFFAOYSA-N

Data: 6 IC50  59 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 64 hits for monomerid = 21724   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	910	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	37	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	753	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	373	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	317	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	510	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	59	n/a	n/a	7.5	22
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	64	n/a	900	n/a	n/a	8.0	22
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	95	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	373	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
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Vitamin D3 receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	70	n/a	n/a	7.2	37
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Bile acid receptor (Human)	BDBM21724 (3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	260	n/a	n/a	n/a	n/a
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