BDBM21725 (1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-ene-5,13-dione::Guggulsterone

SMILES: [H][C@@]12CC(=O)C(=CC)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C

InChI Key: InChIKey=WDXRGPWQVHZTQJ-UHFFFAOYSA-N

Data: 5 KI  9 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 21725   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bile acid receptor (Human)	BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.20E+4	n/a	n/a	7.2	37
TBA									Citation and Details
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Mineralocorticoid receptor (Human)	BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Progesterone receptor (Human)	BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Human)	BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) Show SMILES Show InChI	GoogleScholar	UniChem		37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Progesterone receptor (Human)	BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) Show SMILES Show InChI	GoogleScholar	UniChem		224	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) Show SMILES Show InChI	GoogleScholar	UniChem		252	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) Show SMILES Show InChI	GoogleScholar	UniChem		315	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair