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BDBM217766 US9212182, 1019

SMILES: COc1cc(ccc1-n1c2ccc(cc2ccc1=O)S(=O)(=O)Nc1ccon1)-c1cccc(c1)C#N

InChI Key: InChIKey=UJYCHTMCOOSZIC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 217766   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM217766
PNG
(US9212182, 1019)
Show SMILES COc1cc(ccc1-n1c2ccc(cc2ccc1=O)S(=O)(=O)Nc1ccon1)-c1cccc(c1)C#N
Show InChI InChI=1S/C26H18N4O5S/c1-34-24-15-19(18-4-2-3-17(13-18)16-27)5-8-23(24)30-22-9-7-21(14-20(22)6-10-26(30)31)36(32,33)29-25-11-12-35-28-25/h2-15H,1H3,(H,28,29)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 98n/an/an/an/an/an/a



Amgen Inc

US Patent


Assay Description
HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...


US Patent US9212182 (2015)


BindingDB Entry DOI: 10.7270/Q2TT4PTW
More data for this
Ligand-Target Pair