BDBM218191 6-{[(1r)-1- cyclopropyl- ethyl]amino}- 8-(2,3-dimethyl- phenyl)-7-[4- (trifluoromethyl) benzyl]-7h- purine-2- carboxylic acid::US9540377, 2.59
SMILES C[C@@H](Nc1nc(nc2nc(-c3cccc(C)c3C)n(Cc3ccc(cc3)C(F)(F)F)c12)C(O)=O)C1CC1
InChI Key InChIKey=QIIWMJZOLWTVDS-MRXNPFEDSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 218191
Affinity DataIC50: 147nMT: 2°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair