BDBM218289 6-{[(1r)-1- cyclobutyl- ethyl]amino}- 7-[4-(trifluoro- methyl)benzyl]- 8-[2-(trifluoro- methyl)phenyl]- 7h-purine-2- carboxylic acid::US9540377, 2.79
SMILES C[C@@H](Nc1nc(nc2nc(-c3ccccc3C(F)(F)F)n(Cc3ccc(cc3)C(F)(F)F)c12)C(O)=O)C1CCC1
InChI Key InChIKey=VPUVJGGCCIKOJB-CQSZACIVSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 218289
Affinity DataIC50: 13.4nMT: 2°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair