BDBM218843 US9303033, A1, Example 5

SMILES Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12

InChI Key InChIKey=HNZIQNMBDOAHAU-WCIBSUBMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218843   

TargetCasein kinase II subunit beta(Homo sapiens (Human))
Senhwa Biosciences

US Patent
LigandPNGBDBM218843(US9303033, A1, Example 5)
Affinity DataIC50:  1.18E+3nMpH: 7.0Assay Description:5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase II subunit alpha/beta(Homo sapiens (Human))
Senhwa Biosciences

US Patent
LigandPNGBDBM218843(US9303033, A1, Example 5)
Affinity DataIC50: <0.100nMpH: 7.2Assay Description:In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent