BDBM219294 US9303033, M18, Table 33A, Compound 110

SMILES: O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NN3CCCCC3)nc12

InChI Key: InChIKey=RFHPUZLQSOKRTC-WQLSENKSSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 219294   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II alpha/beta (Homo sapiens (Human)-Rattus norvegicus)	BDBM219294 (US9303033, M18, Table 33A, Compound 110) Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NN3CCCCC3)nc12 Show InChI InChI=1S/C17H21N9O2/c27-14-12(20-17(28)22-14)8-10-9-18-26-13(10)21-15(23-16(26)19-11-4-5-11)24-25-6-2-1-3-7-25/h8-9,11H,1-7H2,(H2,19,21,23,24)(H2,20,22,27,28)/b12-8-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.2	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta) (Homo sapiens (Human))	BDBM219294 (US9303033, M18, Table 33A, Compound 110) Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)nc(NN3CCCCC3)nc12 Show InChI InChI=1S/C17H21N9O2/c27-14-12(20-17(28)22-14)8-10-9-18-26-13(10)21-15(23-16(26)19-11-4-5-11)24-25-6-2-1-3-7-25/h8-9,11H,1-7H2,(H2,19,21,23,24)(H2,20,22,27,28)/b12-8-	PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	>2.50E+3	n/a	n/a	n/a	n/a	7.0	n/a
SENHWA BIOSCIENCES, INC. US Patent					Assay Description 5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 m...				US Patent US9303033 (2016) BindingDB Entry DOI: 10.7270/Q2CN72RX
					More data for this Ligand-Target Pair