BDBM21964 (2S,4R)-4-[(2S)-2-amino-N-hydroxy-5-(1-nitrocarbamimidamido)pentanamido]pyrrolidine-2-carboxamide::N omega-Nitro-L-Arginine-Containing Dipeptide, 5

SMILES N[C@@H](CCCN=C(N)N[N+]([O-])=O)C(=O)N(O)[C@H]1CN[C@@H](C1)C(N)=O

InChI Key InChIKey=CTHMJCQUZVLLJU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21964   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

LigandPNGBDBM21964((2S,4R)-4-[(2S)-2-amino-N-hydroxy-5-(1-nitrocarbam...)
Affinity DataKi:  310nM ΔG°:  -9.02kcal/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

LigandPNGBDBM21964((2S,4R)-4-[(2S)-2-amino-N-hydroxy-5-(1-nitrocarbam...)
Affinity DataKi:  1.60E+4nM ΔG°:  -6.65kcal/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

LigandPNGBDBM21964((2S,4R)-4-[(2S)-2-amino-N-hydroxy-5-(1-nitrocarbam...)
Affinity DataKi:  3.50E+4nM ΔG°:  -6.18kcal/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed