Molecular Structure for 21975

Exiguamine A (4S)-16'-(2-aminoethyl)-9'-hydroxy-1,3,6',6'-tetramethyl-2,5,14',20'-tetraoxo-11'-oxa-6',18'-diazaspiro[imidazolidine-4,12'-pentacyclo[11.7.0.0^{2,10}.0^{3,7}.0^{15,19}]icosane]-1'(13'),2'(10'),3'(7'),8',15'(19'),16'-hexaen-6'-ium

Data: 1 KI

Vconf -m prep

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit in this search
Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
Indoleamine 2,3-Dioxygenase Homo sapiens (human)	Exiguamine A ((4S)-16'-(2-aminoethyl)-9'-hydroxy-1,3,6',6'-tetra...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	41.000	-43.861	n/a	n/a	n/a	6.5	37
University of British Columbia			PC cid PC sid	PubMed	J Med Chem. 51: 2634-7 (2008)