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BDBM219957 US9303033, H44, Table 50A, Compound 39

SMILES: O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)N1CCC(CC1)c1cccc(c1)C#N

InChI Key: InChIKey=RHEVFVQVEVEUDA-JAIQZWGSSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 219957   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Casein kinase II alpha/beta


(Homo sapiens (Human)-Rattus norvegicus)
BDBM219957
PNG
(US9303033, H44, Table 50A, Compound 39)
Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)N1CCC(CC1)c1cccc(c1)C#N
Show InChI InChI=1S/C25H24N8O2/c26-13-15-2-1-3-17(10-15)16-6-8-32(9-7-16)21-12-22(28-19-4-5-19)33-23(30-21)18(14-27-33)11-20-24(34)31-25(35)29-20/h1-3,10-12,14,16,19,28H,4-9H2,(H2,29,31,34,35)/b20-11-
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US Patent
n/an/a<100n/an/an/an/a7.2n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair