Molecular Structure for 220 BindingDB logo
Inhibitor 3 5-{[(4-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl}phenyl)methyl]sulfamoyl}-2-hydroxybenzoic acid

Data:  8 KI

PDB links:  1 PDB IDs contain this monomer as substructures.  1 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits in this search
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
pHTemp
°C
Caspase-4


Homo sapiens (human)
Inhibitor 3
JPEG
(5-{[(4-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl...)
GoogleScholar
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
CSLS
PC cid
PC sid
PubMed
21000-26.699n/an/an/a7.425


Sunesis Pharmaceuticals



J Med Chem. 45: 5005-22 (2002)

Caspase-7


Homo sapiens (human)
Inhibitor 3
JPEG
(5-{[(4-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl...)
B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
CSLS
PC cid
PC sid
PubMed
470.00-36.117n/an/an/a7.425


Sunesis Pharmaceuticals



J Med Chem. 45: 5005-22 (2002)

Caspase-6


Homo sapiens (human)
Inhibitor 3
JPEG
(5-{[(4-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl...)
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
CSLS
PC cid
PC sid
PubMed
1000.0-34.246n/an/an/a7.425


Sunesis Pharmaceuticals



J Med Chem. 45: 5005-22 (2002)

Caspase-5


Homo sapiens (human)
Inhibitor 3
JPEG
(5-{[(4-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl...)
GoogleScholar
KEGG
UniProtKB/TrEMBL
CSLS
PC cid
PC sid
PubMed
12000-28.086n/an/an/a7.425


Sunesis Pharmaceuticals



J Med Chem. 45: 5005-22 (2002)

Caspase-8


Homo sapiens (human)
Inhibitor 3
JPEG
(5-{[(4-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl...)
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
CSLS
PC cid
PC sid
PubMed
150.00-38.948n/an/an/a7.425


Sunesis Pharmaceuticals



J Med Chem. 45: 5005-22 (2002)

Caspase-3


Homo sapiens (human)
Inhibitor 3
JPEG
(5-{[(4-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl...)
B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
CSLS
PC cid
PC sid
PubMed
200.00-38.235n/an/an/a7.425


Sunesis Pharmaceuticals



J Med Chem. 45: 5005-22 (2002)

Caspase-1


Homo sapiens (human)
Inhibitor 3
JPEG
(5-{[(4-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl...)
B.MOAD
DrugBank
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
CSLS
PC cid
PC sid
PubMed
160.00-38.788n/an/an/a7.425


Sunesis Pharmaceuticals



J Med Chem. 45: 5005-22 (2002)

Caspase-2


Homo sapiens (human)
Inhibitor 3
JPEG
(5-{[(4-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl...)
GoogleScholar
KEGG
MMDB
PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
CSLS
PC cid
PC sid
PubMed
9000.0-28.799n/an/an/a7.425


Sunesis Pharmaceuticals



J Med Chem. 45: 5005-22 (2002)