BDBM220123 US9271961, BMT 5-119
SMILES OC(=O)c1ccccc1Nc1cc(ccc1N(=O)=O)C(F)(F)F
InChI Key InChIKey=FZAWUOZTOMHTKK-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 220123
TargetAldo-keto reductase family 1 member C4(Homo sapiens (Human))
University Of Pennsylvania
US Patent
University Of Pennsylvania
US Patent
Affinity DataIC50: 5.50E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Pennsylvania
US Patent
University Of Pennsylvania
US Patent
Affinity DataIC50: 30nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University Of Pennsylvania
US Patent
University Of Pennsylvania
US Patent
Affinity DataIC50: 4.35E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Pennsylvania
US Patent
University Of Pennsylvania
US Patent
Affinity DataIC50: 5.00E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
University Of Pennsylvania
US Patent
University Of Pennsylvania
US Patent
Affinity DataIC50: 4.23E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair