BDBM220123 US9271961, BMT 5-119

SMILES OC(=O)c1ccccc1Nc1cc(ccc1N(=O)=O)C(F)(F)F

InChI Key InChIKey=FZAWUOZTOMHTKK-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 220123   

TargetAldo-keto reductase family 1 member C4(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM220123(US9271961, BMT 5-119)
Affinity DataIC50:  5.50E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM220123(US9271961, BMT 5-119)
Affinity DataIC50:  30nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM220123(US9271961, BMT 5-119)
Affinity DataIC50:  4.35E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM220123(US9271961, BMT 5-119)
Affinity DataIC50: >1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM220123(US9271961, BMT 5-119)
Affinity DataIC50:  5.00E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM220123(US9271961, BMT 5-119)
Affinity DataIC50: >1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM220123(US9271961, BMT 5-119)
Affinity DataIC50:  4.23E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent