BDBM220221 US9290476, 64A::US9290476, 64B::US9290476, 64C

SMILES COc1nc2ccc(cc2c(Cl)c1Cc1ccc(cc1)-n1cncn1)C(O)(c1cncn1C)c1ccc(Cl)cc1

InChI Key InChIKey=BCPPJFGMAGRVIG-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 220221   

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM220221(US9290476, 64A | US9290476, 64B | US9290476, 64C)
Affinity DataKd:  63nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM220221(US9290476, 64A | US9290476, 64B | US9290476, 64C)
Affinity DataKd:  16nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM220221(US9290476, 64A | US9290476, 64B | US9290476, 64C)
Affinity DataKd:  450nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent