BDBM22032 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoquinoline-3-carboxamide::CHEMBL15313::N-(butan-2-yl)-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide::PK 11195::PK-11195::PK11195::RP 52028::[3H]PK 11195

SMILES: CC[C@@H](C)N(C)C(=O)c1cc2ccccc2c(n1)c3ccccc3Cl

InChI Key: InChIKey=RAVIZVQZGXBOQO-UHFFFAOYSA-N

Data: 51 KI  27 IC50  5 Kd

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 83 hits for monomerid = 22032   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Human)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Human)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.82	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.41	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Human)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 3 (Human)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Human)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Human)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		0.780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		0.820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		0.830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		1.06	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		1.14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		1.24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		1.37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		1.41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Translocator protein (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Rat)	BDBM22032 (PK 11195 | PK11195 | RP 52028 | N-(butan-2-yl)-1-(...) Show SMILES Show InChI	GoogleScholar	UniChem		1.88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair