BDBM22042 (3Z)-5-bromo-3-[3-(3-chlorophenyl)-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene]-1,3-dihydro-2H-indol-2-one::1,3-dihydro-2H-indol-2-one, 1::5-[(3Z)-5-bromo-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-3-(3-chlorophenyl)-2-sulfanylidene-1,3-thiazolidin-4-one

SMILES Clc1cccc(c1)N1C(=S)S\C(C1=O)=C1/C(=O)Nc2ccc(Br)cc12

InChI Key InChIKey=LSDJTGQJIZBPMI-YPKPFQOOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 22042   

TargetProtein kinase YpkA(Yersinia pestis)
The Rockefeller University

LigandPNGBDBM22042((3Z)-5-bromo-3-[3-(3-chlorophenyl)-4-oxo-2-thioxo-...)
Affinity DataIC50:  1.81E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed for autophosphorylation and phosphorylation of MBP with radio-labeled gamma-32P. IC50 values were calculated from binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
The Rockefeller University

LigandPNGBDBM22042((3Z)-5-bromo-3-[3-(3-chlorophenyl)-4-oxo-2-thioxo-...)
Affinity DataIC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed for autophosphorylation and phosphorylation of MBP with radio-labeled gamma-32P. IC50 values were calculated from binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
The Rockefeller University

LigandPNGBDBM22042((3Z)-5-bromo-3-[3-(3-chlorophenyl)-4-oxo-2-thioxo-...)
Affinity DataIC50:  2.45E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed for autophosphorylation and phosphorylation of MBP with radio-labeled gamma-32P. IC50 values were calculated from binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed