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BDBM220612 US9296741, 201

SMILES: Cn1cc(-c2cc(ccc2NCC2CCOC2)S(C)(=O)=O)c2cc[nH]c2c1=O

InChI Key:

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 220612   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bromodomain-containing protein 4 (BRD4)(aa 57-168)


(Homo sapiens (Human))
BDBM220612
PNG
(US9296741, 201)
Show SMILES Cn1cc(-c2cc(ccc2NCC2CCOC2)S(C)(=O)=O)c2cc[nH]c2c1=O
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
10.2 -10.9n/an/an/an/an/a6.025



AbbVie Inc

US Patent


Assay Description
A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...


US Patent US9296741 (2016)


BindingDB Entry DOI: 10.7270/Q26W98ZQ
More data for this
Ligand-Target Pair
Bromodomain-containing protein 4 (BRD4)(aa 352-457)


(Homo sapiens (Human))
BDBM220612
PNG
(US9296741, 201)
Show SMILES Cn1cc(-c2cc(ccc2NCC2CCOC2)S(C)(=O)=O)c2cc[nH]c2c1=O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
40.7 -10.1n/an/an/an/an/a6.025



AbbVie Inc

US Patent


Assay Description
A time-resolved fluorescence resonance energy transfer (TR-FRET) assay was used to determine the affinities of compounds of the Examples listed in Ta...


US Patent US9296741 (2016)


BindingDB Entry DOI: 10.7270/Q26W98ZQ
More data for this
Ligand-Target Pair