BDBM220813 US9296759, 79
SMILES NC1=NC2(CCO1)c1cc(Cl)ncc1Oc1ccc(NC(=O)c3ccc(Cl)cn3)cc21
InChI Key InChIKey=CKMFLDNKQHDLRU-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 220813
Affinity DataIC50: 4.00E+5nMpH: 3.5Assay Description:Recombinant CathepsinD was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cathepsi...More data for this Ligand-Target Pair
Affinity DataIC50: 38.6nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair