BDBM220881 US9302986, 32
SMILES CC(C)NS(=O)(=O)c1ccc(OC\C(CN)=C\F)cc1
InChI Key InChIKey=PBHHQZSGADNWMY-YRNVUSSQSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 220881
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:Recombinant human MAO-B (0.06 mg/mL; Sigma Aldrich) was used as source of MAO-B enzyme activities. The assay was performed in a similar way as for hu...More data for this Ligand-Target Pair
TargetAmiloride-sensitive amine oxidase [copper-containing](Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:Recombinant human DAO (2.4 μg/mL) was used as source of DAO enzyme activities. The assay was performed as described in the method for human SSAO/V...More data for this Ligand-Target Pair
TargetMembrane primary amine oxidase(Rattus norvegicus (Rat))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: <1.00E+5nMpH: 7.4Assay Description:Abdominal fat from BALB/c mice, Wistar or Sprague Dawley rats, which are tissues enriched with SSAO/VAP-1-were surgically removed. For every gram of ...More data for this Ligand-Target Pair
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: <1.00E+5nMpH: 7.4Assay Description:Briefly, HMEC cell expressing human SSAO/VAP-1 were grown in several 10 cm petri dishes, once the cells reached 100% confluency, cells were harvested...More data for this Ligand-Target Pair